Bio
Dr. Aadel Chaudhuri, MD, PhD, is Associate Professor and Vice Chair for Translational Research in the Department of Radiation Oncology at the Mayo Clinic in Rochester, Minnesota. He is also Co-Director of the Cancer Individualized Medicine Office across the Mayo Clinic enterprise. Dr. Chaudhuri’s research focuses on cancer genomics and the development and application of liquid biopsy technologies. His laboratory is funded by the National Cancer Institute, the National Institute of General Medical Sciences, the Children’s Discovery Institute, the Children’s Tumor Foundation, and the Melanoma Research Alliance.
Dr. Chaudhuri earned dual undergraduate degrees in Biology and Electrical Engineering & Computer Science from MIT, where he conducted laboratory research studying microRNAs in Nobel Laureate Phillip Sharp’s lab. He then completed his MD at Stanford University and a PhD in Biology at the California Institute of Technology. His PhD work, supervised by Nobel Laureate David Baltimore, explored the roles of microRNAs in the immune system, leading to several highly cited publications. During his residency in Radiation Oncology at Stanford, Dr. Chaudhuri conducted postdoctoral research on circulating tumor DNA (ctDNA) as a biomarker for minimal residual disease (MRD) in lung cancer, which was groundbreaking for the field.
After completing his residency and postdoctoral training at Stanford, Dr. Chaudhuri spent the next six years as a physician-scientist at the Washington University in St. Louis, where he developed and applied an array of different cell-free DNA technologies both in plasma as well as in other biofluids. Recently, Dr. Chaudhuri moved his laboratory to the Mayo Clinic, and has been focusing on cell-free DNA epigenomics and multi-omics to track cancer response vs. resistance to therapy, and cell-free DNA based methods to detect post-treatment minimal residual disease, with liquid biopsy studies focusing on plasma, urine and other biofluids.